B-precursor-ALL of common (c)-ALL subtype - case report 2
Author(s): S. Fruehauf, A. Pitkus, J. Dengler, S. Kraeker
Last change:
2003/04/10
Sort of case report: in clinical view
Medical history: The patient presented complaining of dyspnea, a cough, strong nightsweats and a 5kg weight loss within one week. The patient also had a bleeding inclination with the nose and gums, as well as petechiae on his or her upper arms. A complete blood count (CBC) was ordered to further investigate these symptoms.
Clinical Examination: The CBC results from the initial presentation are shown below. They indicate that the patient was anemic with a hemoglobin of 9.2 g/dl, thrombocytopenic with platelets of 15 /nl, had a leukocytosis of 36.6 /nl and 66% blasts in the peripheral blood. A bone marrow analysis was ordered for further investigation of these hematological abnormalities.
Laboratory results:
Parameter
|
Value
|
Normal value [unit]
|
|---|
RBC
|
3.3
|
12.-16. g/dl
|
Hemoglobin
|
9.2
|
4.3-6.1 /pl
|
Hematocrit
|
0.27
|
0.38-0.52 l/l
|
MCV
|
82
|
83-97 fl
|
Plt
|
15
|
140-440 /nl
|
WBC
|
36.62
|
4.0-10.0 /nl
|
Neutrophils
|
0.73
|
1.8-7.7 /nl
|
Lymphocytes
|
8.06
|
1.0-4.8 /nl
|
Monocytes
|
2.56
|
0.2-0.8 /nl
|
Eosinophils
| |
0-0.5 /nl
|
| | | |
Differential
|
Results
| |
Band Neutrophils
|
1
|
3-10 %
|
Segmented Neutrophils
|
1
|
50-70 %
|
Lymphocytes
| |
25-40 %
|
Atypical Lymphs
| |
0 %
|
Monocytes
|
7
|
2-9 %
|
Eosinophils
| |
2-4 %
|
Basophils
| |
0-1 %
|
Metamyelocytes
|
1
|
0 %
|
Myelocytes
|
2
|
0 %
|
Promyelocytes
| |
0 %
|
Blasts
|
66
|
0 %
|
Normoblasts
| |
/100 L
|
Cytogenetics: Cytogenetics testing showed that the patient has a trisomy 21.
Diagnosis: The findings are typical for an acute lymphoid leukemia of the c-all subtype.
Hematologic Disorders
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